[鸽基因组重复序列的2个转录家族的分离与特性]
[Isolation and characteristics of 2 transcribing families of pigeon-genome repetitive sequences].
作者信息
Gazarian K G, Kuznetsova E D, Tarantul V Z, Zaboĭkina T N
出版信息
Mol Biol (Mosk). 1977 Sep-Oct;11(5):1010-21.
From pigeon DNA two families of repeats have been isolated: one (frequency of repetitions 30--40 times per haploid genome) actively transcribing and the second (frequency of repetitions 2000--2800 times) weakly transcribing in erythroid cells. The reassociation kinetics, GC-content and size of isolated repeats were investigated. Actively transcribing repeats (average length of 350 nucleotides) contain about 55% GC-nucleotides and alternate in the genome with AT-rich sequences of the unique type. Comparison of isolated families of repeats revealed differences in the structure and posttranscriptional fate of RNA transcribed from them.
从鸽子DNA中分离出了两个重复序列家族：一个（每个单倍体基因组重复频率为30 - 40次）在红细胞中活跃转录，另一个（重复频率为2000 - 2800次）在红细胞中弱转录。对分离出的重复序列的重缔合动力学、GC含量和大小进行了研究。活跃转录的重复序列（平均长度为350个核苷酸）含有约55%的GC核苷酸，并在基因组中与独特类型的富含AT的序列交替出现。对分离出的重复序列家族的比较揭示了从它们转录的RNA在结构和转录后命运上的差异。
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