Pennec Y, Ferrec C, Youinou P, Colin J, Mottier D, Jouquan J, Miossec P, Le Menn G
Nouv Presse Med. 1982 Nov 20;11(47):3481-4.
Lysozyme (LZM), immunoglobulins and beta 2-microglobulin concentrations were measured in the saliva of 79 patients with primary (n = 29) or secondary (n = 50) Sjögren's syndrome and in a control population. beta 2-microglobulin and immunoglobulins A, G and M concentrations were higher, and LZM concentrations lower than in controls. A significant correlation was established between LZM and immunoglobulins, but no correlation was found between immunoglobulins and beta 2-microglobulin, nor between the latter and LZM. These results indicate that salivary LZM concentration may be of value in the diagnosis of Sjögren's syndrome.
在79例原发性（n = 29）或继发性（n = 50）干燥综合征患者以及一个对照人群的唾液中，检测了溶菌酶（LZM）、免疫球蛋白和β2-微球蛋白的浓度。与对照组相比，β2-微球蛋白以及免疫球蛋白A、G和M的浓度较高，而LZM浓度较低。LZM与免疫球蛋白之间存在显著相关性，但免疫球蛋白与β2-微球蛋白之间以及β2-微球蛋白与LZM之间均未发现相关性。这些结果表明，唾液LZM浓度可能对干燥综合征的诊断有价值。
