Tarachand U, Sivabalan R, Eapen J
Int J Fertil. 1982;27(4):238-41.
Intraperitoneal administration of cycloheximide (1 mg/kg body weight) to rats immediately after an artificial deciduoma induction inhibits the development of decidual tissue. Besides inhibiting the differentiation of stromal to decidual cells, wet weight and levels of uterine protein and RNA are low following the antibiotic treatment. Injection of the drug (1 mg/kg body weight) into pregnant rats, either on the eve of Day 4 or in the morning of Day 5 of pregnancy, does not prevent implantation but interferes with the growth of embryos.
在人工诱导蜕膜瘤后立即给大鼠腹腔注射环己酰亚胺（1毫克/千克体重）会抑制蜕膜组织的发育。除了抑制基质细胞向蜕膜细胞的分化外，抗生素处理后子宫蛋白质和RNA的湿重及水平也较低。在妊娠第4天前夕或妊娠第5天上午给怀孕大鼠注射该药物（1毫克/千克体重），不会阻止着床，但会干扰胚胎的生长。
