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全身X线照射对大鼠蜕膜瘤形态发生的影响。

Effect of whole-body x-irradiation on the morphogenesis of rat deciduoma.

作者信息

Tarachand U, Sivabalan R, Eapen J

出版信息

Strahlentherapie. 1981 Jul;157(7):474-8.

PMID:7196608
Abstract

Exposure of rats to whole-body X-irradiation (600 R) within 30 minutes of artificial induction of deciduoma resulted in impaired growth of deciduoma involving both endometrium and myometrium. Protein synthesis in endometrium was low 2 days after X-irradiation when compared with unirradiated controls. In addition, levels of RNA and DNA were low in the endometrium of irradiated rats. Development of metrial gland was inhibited in the irradiated rats. The number and morphology of antimesometrial and mesometrial decidual cells were altered in the irradiated animals. Endometrial and myometrial soluble proteins of irradiated rats resolved into fewer bands than those of unirradiated animals.

摘要

在人工诱导蜕膜瘤后30分钟内,将大鼠全身暴露于X射线照射(600伦琴)会导致涉及子宫内膜和肌层的蜕膜瘤生长受损。与未照射的对照组相比,X射线照射后2天,子宫内膜中的蛋白质合成较低。此外,照射大鼠的子宫内膜中RNA和DNA水平较低。照射大鼠的蜕膜腺发育受到抑制。照射动物中,子宫系膜对侧和子宫系膜侧蜕膜细胞的数量和形态发生了改变。照射大鼠的子宫内膜和肌层可溶性蛋白比未照射动物的蛋白条带更少。

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Strahlentherapie. 1981 Jul;157(7):474-8.
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