Karpouzas J, Hatzistilianou M, Kairis M, Dionisopoulou A, Dakou-Voutetakis A
Helv Paediatr Acta. 1982;37(5):465-9.
A granulosa-theca-cell tumour in a 17-month-old girl with isosexual precocity and hirsutism is described. Following removal of the tumour, pubertal signs and hirsutism gradually subsided. Serum alpha-fetoprotein was very high (1800 ng/ml) before, but not any longer detectable after the removal of the tumour and on repeated measurements for the subsequent 34 months, at which time the clinical condition of the child has been very good.
本文描述了一名17个月大患有同性性早熟和多毛症的女孩,其体内存在颗粒-卵泡膜细胞瘤。肿瘤切除后,青春期体征和多毛症逐渐消退。术前血清甲胎蛋白水平非常高(1800 ng/ml),但肿瘤切除后及随后34个月的多次测量中均未再检测到,此时患儿的临床状况良好。