溶血卵磷脂通透处理的小鼠细胞中干扰素作用的持续性
Persistence of interferon action in mouse cells permeabilized with lysolecithin.
作者信息
Lee E J, Sreevalsan T
出版信息
J Virol. 1983 Feb;45(2):895-7. doi: 10.1128/JVI.45.2.895-897.1983.
Abstract
DNA synthesis, as measured by incorporation of [(3)H]TTP, was inhibited in Swiss mouse 3T3 cells treated with interferon and subsequently permeabilized with lysolecithin. The degree of inhibition observed was similar in intact or permeabilized cells. The interferon-induced antiviral state was retained in permeabilized cells.
摘要
通过[（3）H]胸苷三磷酸（TTP）掺入法测定，在用干扰素处理并随后用溶血卵磷脂使其透化的瑞士小鼠3T3细胞中，DNA合成受到抑制。在完整细胞或透化细胞中观察到的抑制程度相似。干扰素诱导的抗病毒状态在透化细胞中得以保留。
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