手术对β2-微球蛋白肾脏排泄的影响。
The effect of surgery on the renal excretion of beta 2-microglobulin.
作者信息
Walenkamp G H, Vree T B, Guelen P J, Jongman-Nix B
出版信息
Clin Chim Acta. 1983 Mar 28;129(1):27-37. doi: 10.1016/0009-8981(83)90148-1.
PMID:6189646
Abstract
Surgical trauma causes an increase in the renal excretion rate of beta 2-microglobulin whilst creatinine excretion is not influenced. The increase in the renal excretion rate of beta 2-microglobulin is probably the result of an increased release of beta 2-microglobulin by the cells which exceeds a maximum in the active tubular reabsorption of the compound by the proximal tubule cell. The renal excretion of beta 2-microglobulin is proportional to the relative clinical trauma score.
摘要
手术创伤会导致β2-微球蛋白的肾脏排泄率增加，而肌酐排泄不受影响。β2-微球蛋白肾脏排泄率的增加可能是由于细胞释放β2-微球蛋白增加，超过了近端小管细胞对该化合物的主动肾小管重吸收的最大值。β2-微球蛋白的肾脏排泄与相对临床创伤评分成正比。
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