• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

白癜风中的角质形成细胞损伤。

Keratinocyte damage in vitiligo.

作者信息

Bhawan J, Bhutani L K

出版信息

J Cutan Pathol. 1983 Jun;10(3):207-12. doi: 10.1111/j.1600-0560.1983.tb00328.x.

DOI:10.1111/j.1600-0560.1983.tb00328.x
PMID:6190850
Abstract

Light and electron-microscopic studies were performed on the amelanotic and adjacent normal-appearing skin in patients with vitiligo. The amelanotic skin revealed complete loss of pigment and absence of melanocytes. In addition to severe degenerative changes of melanocytes, varying degree of damage was also seen in the keratinocytes of normal-appearing skin adjacent to amelanotic skin.

摘要

对白癜风患者的无色素皮肤及相邻外观正常的皮肤进行了光镜和电镜研究。无色素皮肤显示色素完全丧失且黑素细胞缺失。除黑素细胞的严重退行性改变外,在无色素皮肤相邻的外观正常皮肤的角质形成细胞中也可见不同程度的损伤。

相似文献

1
Keratinocyte damage in vitiligo.白癜风中的角质形成细胞损伤。
J Cutan Pathol. 1983 Jun;10(3):207-12. doi: 10.1111/j.1600-0560.1983.tb00328.x.
2
Epidermal changes in active vitiligo.活动期白癜风的表皮变化。
J Dermatol. 1992 Apr;19(4):217-22. doi: 10.1111/j.1346-8138.1992.tb03211.x.
3
Ultrastructural and functional alterations of mitochondria in perilesional vitiligo skin.白癜风皮损周围皮肤线粒体的超微结构和功能改变
J Dermatol Sci. 2009 Jun;54(3):157-67. doi: 10.1016/j.jdermsci.2009.02.004. Epub 2009 Mar 17.
4
Effect of PUVA therapy on melanocytes and keratinocytes in non-segmental vitiligo: histopathological, immuno-histochemical and ultrastructural study.PUVA 疗法对非节段性白癜风黑素细胞和角质形成细胞的影响:组织病理学、免疫组织化学和超微结构研究。
Photodermatol Photoimmunol Photomed. 2012 Feb;28(1):17-25. doi: 10.1111/j.1600-0781.2011.00631.x.
5
Ultrastructural study of vitiligo.
Int J Dermatol. 1993 Apr;32(4):269-71. doi: 10.1111/ijd.1993.32.4.269.
6
Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo.泛发性白癜风患者非皮损区皮肤摩擦后黑素细胞脱离
Br J Dermatol. 2003 Jan;148(1):95-101. doi: 10.1046/j.1365-2133.2003.05024.x.
7
Immunolocalization of tenascin-C in vitiligo.白癜风中肌腱蛋白-C的免疫定位
Appl Immunohistochem Mol Morphol. 2012 Oct;20(5):501-11. doi: 10.1097/PAI.0b013e318246c793.
8
[Quantitative ultrastructural study of the epidermis basal layer in the vitiligo patches and in the marginal hyperchromic and normal skin (author's transl)].
Ann Dermatol Venereol. 1978 Apr;105(4):395-400.
9
Absence of Merkel cells in lesional skin of vitiligo [corrected].
Int J Dermatol. 1994 Jul;33(7):481-3. doi: 10.1111/j.1365-4362.1994.tb02859.x.
10
The melanocytorrhagic hypothesis of vitiligo tested on pigmented, stressed, reconstructed epidermis.白癜风的黑素细胞出血假说在色素沉着、应激、重建的表皮上进行测试。
Pigment Cell Res. 2007 Oct;20(5):385-93. doi: 10.1111/j.1600-0749.2007.00396.x.

引用本文的文献

1
Melanocyte-keratinocyte cross-talk in vitiligo.白癜风中黑素细胞与角质形成细胞的相互作用
Front Med (Lausanne). 2023 May 19;10:1176781. doi: 10.3389/fmed.2023.1176781. eCollection 2023.
2
Update on the pathogenesis of vitiligo.白癜风发病机制的最新研究进展。
An Bras Dermatol. 2022 Jul-Aug;97(4):478-490. doi: 10.1016/j.abd.2021.09.008. Epub 2022 May 25.
3
Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases.过氧化氢酶在氧化应激和与年龄相关的退行性疾病中的作用。
Oxid Med Cell Longev. 2019 Nov 11;2019:9613090. doi: 10.1155/2019/9613090. eCollection 2019.
4
Novel approaches to vitiligo treatment via modulation of mTOR and NF-κB pathways in human skin melanocytes.通过调节人皮肤黑素细胞中的mTOR和NF-κB信号通路治疗白癜风的新方法。
Int J Biol Sci. 2017 Feb 25;13(3):391-400. doi: 10.7150/ijbs.17318. eCollection 2017.
5
Aquaporin 3 and E-Cadherin Expression in Perilesional Vitiligo Skin.水通道蛋白3和E-钙黏蛋白在白癜风皮损周围皮肤中的表达
J Clin Diagn Res. 2016 Dec;10(12):WC01-WC06. doi: 10.7860/JCDR/2016/22730.8959. Epub 2016 Dec 1.
6
Role of keratinocytes in the development of vitiligo.角质形成细胞在白癜风发病中的作用。
Ann Dermatol. 2012 May;24(2):115-25. doi: 10.5021/ad.2012.24.2.115. Epub 2012 Apr 26.
7
Comparison of plasma malondialdehyde, glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls.白癜风患者与健康对照者血浆丙二醛、谷胱甘肽、谷胱甘肽过氧化物酶、羟脯氨酸和硒水平的比较。
Indian J Dermatol. 2008;53(3):106-10. doi: 10.4103/0019-5154.39577.
8
Increased monoamine oxidase A activity in the epidermis of patients with vitiligo.白癜风患者表皮中单胺氧化酶A活性增加。
Arch Dermatol Res. 1996;288(1):14-8. doi: 10.1007/BF02505037.
9
Increased in vitro expression of beta 2-adrenoceptors in differentiating lesional keratinocytes of vitiligo patients.
Arch Dermatol Res. 1993;285(4):216-20. doi: 10.1007/BF00372012.
10
Catechol-O-methyltransferase in vitiligo.白癜风中的儿茶酚-O-甲基转移酶
Arch Dermatol Res. 1994;286(2):81-6. doi: 10.1007/BF00370732.