Ronai Z, Sulitzeanu D
Clin Immunol Immunopathol. 1983 Mar;26(3):327-34. doi: 10.1016/0090-1229(83)90117-4.
It has been previously shown that rats injected with red blood cells (RBC) infected with Plasmodium berghei make autoantibodies reacting with normal rat RBC as demonstrated by a staphylococcal protein A binding assay. In this study, the serum of the infected rats was found to contain also antibodies to several other types of rat cells (lymphoid, liver, and kidney cells and brain tissue) as well as against RBC and lymphoid cells of mice and sheep, but not of man. Rat, mouse, and sheep RBC and rat and mouse lymphocytes absorbed completely the antibodies to rat RBC, suggesting that a single, cross-reacting determinant might be involved in these reactions.
先前的研究表明，注射感染了伯氏疟原虫的红细胞（RBC）的大鼠会产生自身抗体，该抗体可与正常大鼠红细胞发生反应，这已通过葡萄球菌蛋白A结合试验得到证实。在本研究中，发现感染大鼠的血清中还含有针对其他几种类型大鼠细胞（淋巴细胞、肝细胞、肾细胞和脑组织）以及小鼠和绵羊的红细胞与淋巴细胞的抗体，但不含有针对人类细胞的抗体。大鼠、小鼠和绵羊的红细胞以及大鼠和小鼠的淋巴细胞完全吸收了针对大鼠红细胞的抗体，这表明这些反应可能涉及单一的交叉反应决定簇。
