免疫组织化学显示骶尾部畸胎瘤中胰腺组织功能分化的改变

Immunohistochemical demonstration of altered functional differentiation of pancreatic tissue in sacrococcygeal teratomas.

作者信息

Hodes J E, Hull M T, Mirkin L D, Hodes M E

出版信息

Hum Pathol. 1983 Aug;14(8):724-6. doi: 10.1016/s0046-8177(83)80146-4.

PMID:6192072

Abstract

The finding of teratomas with mature-appearing pancreatic tissue showing abnormal production of immunoreactive amylase appears to contradict earlier suggestions that somatic tissue in teratomas that appears mature also functions normally. It therefore seems judicious to study carefully both morphologic and functional characteristics of tissues in teratomas before utilizing them as experimental models of tissue differentiation, since at least in the case of human amylase, functional differentiation does not always follow morphologic differentiation.

摘要

畸胎瘤中出现成熟外观的胰腺组织且显示免疫反应性淀粉酶产生异常，这一发现似乎与早期观点相矛盾，早期观点认为畸胎瘤中外观成熟的体细胞组织功能也正常。因此，在将畸胎瘤组织用作组织分化的实验模型之前，仔细研究其形态学和功能特征似乎是明智的，因为至少就人淀粉酶而言，功能分化并不总是伴随形态学分化。