Tanizaki Y, Komagoe H, Sudo M, Ohtani J, Kimura I, Akagi K, Townley R G
Acta Med Okayama. 1983 Jun;37(3):207-11. doi: 10.18926/AMO/32436.
45Ca uptake and histamine release was examined in mast cells from rats sensitized with ovalbumin and Bordetella Bertussis as an adjuvant. The uptake of 45Ca by the mast cells was significantly increased by stimulation with ovalbumin as was the release of histamine from the mast cells. Nifedipine, a calcium antagonist, inhibited the increase in both 45Ca uptake and histamine release stimulated by ovalbumin, though the effect on 45Ca uptake was stronger than that on histamine release.
以卵清蛋白致敏并用百日咳博德特氏菌作为佐剂的大鼠肥大细胞,对其45Ca摄取和组胺释放进行了检测。用卵清蛋白刺激后,肥大细胞对45Ca的摄取以及肥大细胞中组胺的释放均显著增加。钙拮抗剂硝苯地平抑制了由卵清蛋白刺激引起的45Ca摄取和组胺释放的增加,尽管其对45Ca摄取的影响比对组胺释放的影响更强。