Reuther K, Aagaard J, Jensen K S
Br J Urol. 1983 Oct;55(5):493-4. doi: 10.1111/j.1464-410x.1983.tb03355.x.
Detrusor instability in infravesical obstruction is well recognised and often resolves after surgery. The aetiology is not clearly understood but is probably due to increased vesical sensory input. Since intravesical lignocaine has been proved to have an effect (although shortlived) on detrusor instability in some patients, we have used it in order to differentiate between idiopathic detrusor instability and detrusor instability caused by infravesical obstruction. Our study showed that in patients with a positive lignocaine test pre-operatively, the detrusor instability and micturition disorder disappeared after operation, and in patients with a negative lignocaine test, it persisted. The differences were statistically significant (P less than 0.5).
膀胱出口梗阻所致逼尿肌不稳定已得到充分认识，且常在术后缓解。其病因尚不清楚，但可能是由于膀胱感觉传入增加所致。由于膀胱内利多卡因已被证明对某些患者的逼尿肌不稳定有作用（尽管作用短暂），我们使用它来鉴别特发性逼尿肌不稳定和膀胱出口梗阻所致的逼尿肌不稳定。我们的研究表明，术前利多卡因试验阳性的患者，术后逼尿肌不稳定和排尿障碍消失；而利多卡因试验阴性的患者，这些症状持续存在。差异具有统计学意义（P小于0.5）。
