Grieger M, Siems W, Müller M, Grinberg L, Leppin K
Folia Haematol Int Mag Klin Morphol Blutforsch. 1983;110(4):581-93.
By using the model of infection with plasmodium berghei in white mice the attempt was made to explain the oxidative damages of red blood cells as a cause for haemolysis. In addition to a diminished new formation of erythrocytes there was an increased cell lysis under the impact of infection. Without any changes of the Met-Hb-percentage and of Heinz bodies an increase of GSH and GSSG could be measured. The conclusion was drawn that a damage of red blood cells caused by oxidation may occur by changing the relation of reduced tripeptides to oxidised ones.
通过使用伯氏疟原虫感染小白鼠的模型，试图解释红细胞的氧化损伤是溶血的一个原因。除了红细胞生成减少外，感染的影响下细胞裂解增加。在高铁血红蛋白百分比和海因茨小体没有任何变化的情况下，可以测量到谷胱甘肽（GSH）和氧化型谷胱甘肽（GSSG）增加。得出的结论是，氧化引起的红细胞损伤可能是通过改变还原型三肽与氧化型三肽的比例而发生的。
