免疫兔血清无法识别持续感染期间分离出的山羊关节炎-脑炎病毒的抗原变体。
Immune rabbit sera do not recognize antigenic variants of caprine arthritis-encephalitis virus isolated during persistent infection.
作者信息
Anderson L W, Klevjer-Anderson P, McGuire T C
出版信息
Infect Immun. 1983 Nov;42(2):845-7. doi: 10.1128/iai.42.2.845-847.1983.
Abstract
Isolates of caprine arthritis-encephalitis virus recovered 12 to 18 months after infection of goats were tested for neutralization by using rabbit antisera directed to the original inoculum virus. Only slight differences in neutralization kinetics between the long-term isolates and the original virus were detected, indicating that heterologous rabbit antisera do not detect antigenic variation of the neutralizing epitopes of caprine arthritis-encephalitis virus.
摘要
用针对原始接种病毒的兔抗血清对山羊感染12至18个月后分离出的山羊关节炎-脑炎病毒进行中和试验。长期分离株与原始病毒之间仅检测到中和动力学的细微差异，这表明异种兔抗血清未检测到山羊关节炎-脑炎病毒中和表位的抗原变异。
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Animal virus infections that defy vaccination: equine infectious anemia, caprine arthritis-encephalitis, maedi-visna, and feline infectious peritonitis.难以通过疫苗接种预防的动物病毒感染：马传染性贫血、山羊关节炎-脑炎、梅迪-维斯纳病和猫传染性腹膜炎。
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Antigenic variation of neutralization-sensitive epitopes of caprine arthritis-encephalitis lentivirus during persistent arthritis.山羊关节炎-脑炎慢病毒持续关节炎期间中和敏感表位的抗原变异
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本文引用的文献
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Characterization of the infection of caprine synovial membrane cells by the retrovirus caprine arthritis-encephalitis virus.
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Preferential immune response to virion surface glycoproteins by caprine arthritis-encephalitis virus-infected goats.山羊关节炎-脑炎病毒感染的山羊对病毒粒子表面糖蛋白的优先免疫反应。
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Neutralizing antibody response of rabbits and goats to caprine arthritis-encephalitis virus.兔和山羊对山羊关节炎-脑炎病毒的中和抗体反应。
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Chronic arthritis in goats caused by a retrovirus.由逆转录病毒引起的山羊慢性关节炎。
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Antigenic drift of equine infectious anemia virus in chronically infected horses.慢性感染马中马传染性贫血病毒的抗原漂移
Arch Gesamte Virusforsch. 1973;41(1):1-10. doi: 10.1007/BF01249923.
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Antigenic drift in influenza A viruses. I. Selection and characterization of antigenic variants of A/PR/8/34 (HON1) influenza virus with monoclonal antibodies.甲型流感病毒的抗原漂移。I. 用单克隆抗体对A/PR/8/34（H1N1）流感病毒抗原变体的筛选与鉴定
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Antigenic variation in visna virus.维斯纳病毒的抗原变异
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