Choi B H, Kim R C
Science. 1984 Jan 27;223(4634):407-9. doi: 10.1126/science.6197755.
In the human fetal spinal cord at 15 to 16 weeks, glial fibrillary acidic protein (GFAP) was demonstrated within the cytoplasm and processes of cells having the cytological, ultrastructural, and immunocytochemical features of oligodendrocytes--including processes that extend into and contribute to the formation of myelin sheaths. By 17 to 18 weeks, however, GFAP immunoreactivity was no longer evident within such cells. Thus GFAP is expressed by myelin-forming oligodendroglia early in their development.
在15至16周的人类胎儿脊髓中，在具有少突胶质细胞的细胞学、超微结构和免疫细胞化学特征的细胞的细胞质和突起内发现了胶质纤维酸性蛋白（GFAP），这些突起延伸到髓鞘并参与髓鞘的形成。然而，到17至18周时，此类细胞内的GFAP免疫反应性不再明显。因此，GFAP在形成髓鞘的少突胶质细胞发育早期表达。
