无皮质类固醇联合化疗引起的骨缺血性坏死。
Avascular necrosis of bone caused by combination chemotherapy without corticosteroids.
作者信息
Harper P G, Trask C, Souhami R L
出版信息
Br Med J (Clin Res Ed). 1984 Jan 28;288(6413):267-8. doi: 10.1136/bmj.288.6413.267.
Abstract
Avascular necrosis of bone is sometimes a complication of cancer chemotherapy that includes corticosteroids but generally occurs at a single site. A patient with testicular teratoma who received chemotherapy that did not include steroids developed avascular necrosis of the left femoral head, left scaphoid, and both medial femoral condyles. Symptoms were relieved with anti-inflammatory drugs and physiotherapy. This case indicates that avascular necrosis may be caused by cancer chemotherapy that does not include steroids.
摘要
骨缺血性坏死有时是包括皮质类固醇在内的癌症化疗的一种并发症，但通常发生在单一部位。一名患有睾丸畸胎瘤的患者接受了不包括类固醇的化疗，却出现了左侧股骨头、左侧舟状骨和双侧股骨内侧髁的缺血性坏死。症状通过抗炎药物和物理治疗得到缓解。该病例表明，不包括类固醇的癌症化疗可能导致骨缺血性坏死。
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