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1
Avascular necrosis of bone caused by combination chemotherapy without corticosteroids.无皮质类固醇联合化疗引起的骨缺血性坏死。
Br Med J (Clin Res Ed). 1984 Jan 28;288(6413):267-8. doi: 10.1136/bmj.288.6413.267.
2
Avascular necrosis in patients treated with BEP chemotherapy for testicular tumours.接受BEP化疗治疗睾丸肿瘤的患者发生的无血管性坏死。
Clin Oncol (R Coll Radiol). 1999;11(2):126-7. doi: 10.1053/clon.1999.9027.
3
Avascular necrosis in patients treated with BEP chemotherapy for testicular tumours.接受BEP化疗治疗睾丸肿瘤的患者发生的无血管性坏死。
Clin Oncol (R Coll Radiol). 2000;12(1):69. doi: 10.1053/clon.2000.9117.
4
Nontraumatic osteonecrosis after chemotherapy for testicular cancer: a systematic review.
Am J Clin Oncol. 2001 Dec;24(6):603-6. doi: 10.1097/00000421-200112000-00015.
5
Osteonecrosis of bone associated with combination chemotherapy without corticosteroids.与不含皮质类固醇的联合化疗相关的骨坏死
Clin Orthop Relat Res. 1986 Mar(204):150-3.
6
The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours.睾丸肿瘤化疗患者中无血管性坏死的患病率。
Br J Cancer. 2001 Nov 30;85(11):1624-6. doi: 10.1054/bjoc.2001.2155.
7
Avascular necrosis of bone: the hidden risk of glucocorticoids used as antiemetics in cancer chemotherapy.骨缺血性坏死:糖皮质激素在癌症化疗中用作止吐药的潜在风险。
Int J Clin Pract. 2001 Jun;55(5):344-5.
8
Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.睾丸癌采用顺铂、长春碱和博来霉素治疗后出现短暂性左侧同向性偏盲和脑病。
J Clin Oncol. 1983 Jun;1(6):392-3. doi: 10.1200/JCO.1983.1.6.392.
9
Second malignancy after cisplatin, vinblastine, and bleomycin (PVB) chemotherapy: a case report.顺铂、长春碱和博来霉素(PVB)化疗后发生的第二原发性恶性肿瘤:一例报告。
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10
Hemorrhagic cystitis after i.v. bleomycin, vinblastine, cisplatin, and etoposide for testicular cancer.静脉注射博来霉素、长春花碱、顺铂和依托泊苷治疗睾丸癌后发生的出血性膀胱炎。
Cancer Treat Rep. 1986 Apr;70(4):548-9.

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Atraumatic elbow avascular necrosis in the adult is rare, multifocal, and associated with systemic corticosteroid use.成人创伤性肘关节缺血性坏死罕见、多灶性且与全身使用皮质类固醇有关。
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Avascular necrosis of femoral head - Demographic profile, natural history of asymptomatic hips and native hip survivorship in an indian subcontinent cohort.股骨头缺血性坏死——印度次大陆队列中的人口统计学特征、无症状髋关节的自然病史及天然髋关节生存率
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Risk factors for osteonecrosis of the femoral head in brain tumor patients receiving corticosteroid after surgery.脑肿瘤术后接受皮质类固醇治疗的患者发生股骨头坏死的危险因素。
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Toxicities Associated with Cisplatin-Based Chemotherapy and Radiotherapy in Long-Term Testicular Cancer Survivors.长期睾丸癌幸存者中与顺铂为基础的化疗和放疗相关的毒性反应
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Relative volume measured with magnetic resonance imaging is an articular collapse predictor in hematological pediatric patients with femoral head osteonecrosis.采用磁共振成像测量的相对体积是患有股骨头坏死的血液学儿科患者关节塌陷的预测指标。
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Multimodality treatment of a complex series of parallel pathologies in a 16-year-old male that ultimately leads to bilateral hip arthroplasty surgery: A case report.一名16岁男性复杂系列并行病变的多模态治疗,最终导致双侧髋关节置换手术:病例报告。
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Role of genetic susceptibility in development of treatment-related adverse outcomes in cancer survivors.遗传易感性在癌症幸存者治疗相关不良结局发展中的作用。
Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2048-67. doi: 10.1158/1055-9965.EPI-11-0659.
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Complications associated with chemotherapy in testicular cancer management.睾丸癌治疗中与化疗相关的并发症。
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9
Potential pathophysiological mechanisms in osteonecrosis of the jaw.颌骨骨坏死的潜在病理生理学机制。
Ann N Y Acad Sci. 2011 Feb;1218:62-79. doi: 10.1111/j.1749-6632.2010.05835.x.
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Vascularized bone grafts and their applications in the treatment of carpal pathology.带血管骨移植及其在手外科疾病治疗中的应用。
Semin Plast Surg. 2008 Aug;22(3):213-27. doi: 10.1055/s-2008-1081404.

本文引用的文献

1
Avascular necrosis of bone complicating treatment of malignant lymphoma.恶性淋巴瘤治疗并发的骨缺血性坏死。
Am J Med. 1981 Nov;71(5):751-8. doi: 10.1016/0002-9343(81)90354-5.
2
Avascular necrosis of bone after renal transplantation.
J Bone Joint Surg Am. 1971 Mar;53(2):203-15.
3
Osteonecrosis of the femoral head in patients with lymphoma treated with intermittent combination chemotherapy (including corticosteroids).接受间歇性联合化疗(包括使用皮质类固醇)治疗的淋巴瘤患者的股骨头坏死
Cancer. 1975 Nov;36(5):1585-8. doi: 10.1002/1097-0142(197511)36:5<1585::aid-cncr2820360508>3.0.co;2-d.
4
Osteonecrosis in Hodgkin's disease.霍奇金病中的骨坏死。
Br J Radiol. 1978 May;51(605):328-32. doi: 10.1259/0007-1285-51-605-328.
5
Osteonecrosis after chemotherapy.化疗后骨坏死
Lancet. 1978 Jun 17;1(8077):1316. doi: 10.1016/s0140-6736(78)91306-5.

无皮质类固醇联合化疗引起的骨缺血性坏死。

Avascular necrosis of bone caused by combination chemotherapy without corticosteroids.

作者信息

Harper P G, Trask C, Souhami R L

出版信息

Br Med J (Clin Res Ed). 1984 Jan 28;288(6413):267-8. doi: 10.1136/bmj.288.6413.267.

DOI:10.1136/bmj.288.6413.267
PMID:6198019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1444026/
Abstract

Avascular necrosis of bone is sometimes a complication of cancer chemotherapy that includes corticosteroids but generally occurs at a single site. A patient with testicular teratoma who received chemotherapy that did not include steroids developed avascular necrosis of the left femoral head, left scaphoid, and both medial femoral condyles. Symptoms were relieved with anti-inflammatory drugs and physiotherapy. This case indicates that avascular necrosis may be caused by cancer chemotherapy that does not include steroids.

摘要

骨缺血性坏死有时是包括皮质类固醇在内的癌症化疗的一种并发症,但通常发生在单一部位。一名患有睾丸畸胎瘤的患者接受了不包括类固醇的化疗,却出现了左侧股骨头、左侧舟状骨和双侧股骨内侧髁的缺血性坏死。症状通过抗炎药物和物理治疗得到缓解。该病例表明,不包括类固醇的癌症化疗可能导致骨缺血性坏死。