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免疫脾细胞培养上清液中的一种体液因子对抗原特异性迟发型超敏反应的增强作用。

Antigen-specific augmentation of delayed-type hypersensitivity by a humoral factor in the culture supernatant of immune spleen cells.

作者信息

Yamada A, Himeno K, Kumazawa Y, Nomoto K

出版信息

Cell Immunol. 1984 Mar;84(1):206-9. doi: 10.1016/0008-8749(84)90092-3.

Abstract

Supernatants were harvested from a 24-hr culture of immune mouse spleen cells and erythrocyte antigens. Delayed footpad reactions to such heterologous erythrocytes were augmented antigen specifically when the supernatants were transferred a few hours before immunization of recipients. The augmentation factor(s) contained in the supernatants may exert its effect on the induction phase of delayed-type hypersensitivity.

摘要

从免疫小鼠脾细胞与红细胞抗原培养24小时的培养物中收获上清液。当在受体免疫前数小时转移上清液时,对这种异源红细胞的迟发型足垫反应会抗原特异性增强。上清液中所含的增强因子可能对迟发型超敏反应的诱导阶段发挥作用。

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