Hadfield S G, Glynn A A
Immunology. 1984 Mar;51(3):615-21.
The technique of immuno-blotting was used to examine the specificity of serum antibodies in patients with gonorrhoea and to define the significant antigenic determinant present in the desoxycholate extracts of gonococcal cell walls used previously for serological diagnosis. IgG but not IgA antibody was directed predominantly against lipopolysaccharide. Antibodies to outer membrane proteins were not found as frequently as expected. There was a suggestion from the results that antibodies to antigen PI was more common in systemic than in local infections.
采用免疫印迹技术检测淋病患者血清抗体的特异性，并确定先前用于血清学诊断的淋球菌细胞壁脱氧胆酸盐提取物中存在的重要抗原决定簇。主要针对脂多糖的是IgG抗体而非IgA抗体。针对外膜蛋白的抗体不像预期的那样常见。结果提示，抗原PI抗体在全身性感染中比在局部感染中更常见。
