[Ⅰ型糖尿病中β-血小板球蛋白与代谢代偿之间的相关性]

[Correlation between beta-thromboglobulin and metabolic compensation in diabetes type I].

作者信息

Gragnoli G, Signorini A M, Tanganelli I

出版信息

Ric Clin Lab. 1983;13 Suppl 3:383-7.

PMID:6200916

Abstract

In 37 type I diabetic out-patients without any apparent vascular complication and in 9 diabetics with ketoacidosis we have studied the behavior of beta-TG and of glycemia, GSP and HbA1 which are indexes of the short, medium and long-term glycemic control, respectively. In the out-patients beta-TG was found to be correlated only with the GSP. During the recovery of glycemic control, a progressive decrease in the level of beta-TG was found. Therefore, we conclude that also the metabolic derangement of diabetes takes part in the platelet activation.

摘要

在37例无明显血管并发症的Ⅰ型糖尿病门诊患者以及9例酮症酸中毒糖尿病患者中，我们研究了β-血小板球蛋白（beta-TG）以及血糖、糖化血清蛋白（GSP）和糖化血红蛋白A1（HbA1）的变化情况，这些指标分别代表短期、中期和长期血糖控制水平。在门诊患者中，发现β-血小板球蛋白仅与糖化血清蛋白相关。在血糖控制恢复过程中，发现β-血小板球蛋白水平逐渐下降。因此，我们得出结论，糖尿病的代谢紊乱也参与了血小板活化过程。