T细胞Ly1和Ly23亚类的独立分化途径。去除特定T细胞亚类的小鼠的实验制备。
Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses.
作者信息
Huber B, Cantor H, Shen F W, Boyse E A
出版信息
J Exp Med. 1976 Oct 1;144(4):1128-33. doi: 10.1084/jem.144.4.1128.
Abstract
When B mice are supplied with Ly1 or Ly23 cells they acquire, over the next 6 mo, only the immune functions associated with each of these T-cell subclasses, respectively. The T-cell population of these "B-Ly1" and "B-Ly23" mice mice also remains restricted to the Ly1 and Ly23 subclass phenotypes. Thus the Ly1 and Ly23 populations are derived from two separate lines of differentiation and are not sequential stages of a single differentiative pathway.
摘要
当向B小鼠提供Ly1或Ly23细胞时，在接下来的6个月里，它们分别仅获得与这些T细胞亚类各自相关的免疫功能。这些“B-Ly1”和“B-Ly23”小鼠的T细胞群体也仍然局限于Ly1和Ly23亚类表型。因此，Ly1和Ly23群体源自两条独立的分化谱系，而不是单一分化途径的连续阶段。
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本文引用的文献
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2
Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity.带有不同Ly抗原的T淋巴细胞功能亚类。II. Ly+细胞亚类在杀伤活性产生中的合作。
J Exp Med. 1975 Jun 1;141(6):1390-9. doi: 10.1084/jem.141.6.1390.
3
Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.带有不同Ly抗原的T淋巴细胞功能亚类。I. 功能不同的T细胞亚类的产生是一个独立于抗原的分化过程。
J Exp Med. 1975 Jun 1;141(6):1376-89. doi: 10.1084/jem.141.6.1376.
4
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J Exp Med. 1976 Jun 1;143(6):1391-40. doi: 10.1084/jem.143.6.1391.
5
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J Exp Med. 1976 Jun 1;143(6):1382-90. doi: 10.1084/jem.143.6.1382.
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