Uriel J, Villacampa M J, Moro R, Naval J, Failly-Crépin C
C R Seances Acad Sci III. 1983;297(13):589-92.
Radiolabelled alphafetoprotein (AFP) was selectively concentrated by spontaneous mammary carcinomas of the Mouse. External photoscans of Mice injected with 131I-AFP confirmed the significant accumulation of the protein in the tumors. These results prove the usefulness of AFP as a radiotracer for mammary carcinomas and represent a novel approach for tumor detection.
放射性标记的甲胎蛋白(AFP)被小鼠自发性乳腺癌选择性富集。对注射了¹³¹I-AFP的小鼠进行的体外光扫描证实了该蛋白在肿瘤中的显著蓄积。这些结果证明了AFP作为乳腺癌放射性示踪剂的有用性,并代表了一种肿瘤检测的新方法。