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二价铜与葡聚糖的3-巯基-2-羟丙基醚复合物(C-79)的抗感染特性

Anti-infectious properties of the complex of bivalent copper with 3-mercapto-2-hydroxypropyl ether of dextran (C-79).

作者信息

Wieczorek Z, Kowalewska D, Giełdanowski J, Zimecki M, Mioduszewski J Z

出版信息

Arch Immunol Ther Exp (Warsz). 1983;31(5):701-5.

PMID:6202275
Abstract

The anti-infectious activity of the C-79 preparation was examined on mice intravenously infected with Shigella sonnei dysentery of phase I. The activity of the preparation was determined taking into account the number of bacteria cultured from the organs of the examined animals and the number of animals surviving the infection as compared with the control. C-79 preparation administered to the mice before the infection was observed to protect then from death almost in 100%. The activity of the preparation differed according to the strategy of administration.

摘要

研究了C - 79制剂对静脉注射感染I相宋内志贺氏菌痢疾的小鼠的抗感染活性。通过考虑从受试动物器官培养出的细菌数量以及与对照组相比在感染中存活的动物数量来确定该制剂的活性。观察到在感染前给小鼠施用C - 79制剂可使它们几乎100%免于死亡。该制剂的活性因给药策略而异。

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Anti-infectious properties of the complex of bivalent copper with 3-mercapto-2-hydroxypropyl ether of dextran (C-79).二价铜与葡聚糖的3-巯基-2-羟丙基醚复合物(C-79)的抗感染特性
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Immunobiological properties of the complex of bivalent copper with 3-mercapto-2-hydroxypropyl ether of dextran (C-79).二价铜与葡聚糖的3-巯基-2-羟丙基醚复合物(C-79)的免疫生物学特性
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[Changes in the degree of sensitivity to antibiotics of Shigella isolated from patients with dysentery in a city infectious disease hospital over the past 8 years].[某城市传染病医院过去8年中从痢疾患者分离出的志贺菌对抗生素敏感性程度的变化]
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New dextran derivatives. II. Preparation of compounds of copper (II) with 3-mercapto-2-hydroxypropyl ether of dextran.新型葡聚糖衍生物。II. 葡聚糖的3-巯基-2-羟丙基醚与铜(II)化合物的制备。
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Immune processes in the course of infection with dysentery bacilli. I. Transfer of immunity by means of spleen cells.痢疾杆菌感染过程中的免疫过程。一、通过脾细胞进行免疫转移。
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