Wieczorek Z, Kowalewska D, Giełdanowski J, Zimecki M, Mioduszewski J Z
Arch Immunol Ther Exp (Warsz). 1983;31(5):701-5.
The anti-infectious activity of the C-79 preparation was examined on mice intravenously infected with Shigella sonnei dysentery of phase I. The activity of the preparation was determined taking into account the number of bacteria cultured from the organs of the examined animals and the number of animals surviving the infection as compared with the control. C-79 preparation administered to the mice before the infection was observed to protect then from death almost in 100%. The activity of the preparation differed according to the strategy of administration.
研究了C - 79制剂对静脉注射感染I相宋内志贺氏菌痢疾的小鼠的抗感染活性。通过考虑从受试动物器官培养出的细菌数量以及与对照组相比在感染中存活的动物数量来确定该制剂的活性。观察到在感染前给小鼠施用C - 79制剂可使它们几乎100%免于死亡。该制剂的活性因给药策略而异。