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用异丙肌苷治疗的热损伤豚鼠的免疫反应。

Immune response in thermally injured guinea-pigs treated with methisoprinol.

作者信息

Castelli A, Sbano E, Fimiani M, Francini G, Andreassi L, Gennari C

出版信息

Int J Tissue React. 1984;6(2):123-6.

PMID:6203860
Abstract

A series of experiments has been performed in order to evaluate the effects of methisoprinol on immune response following thermal injury. Methisoprinol treatment induced a sharp stimulation of the cell-mediated immune response in burned animals. This finding demonstrates that methisoprinol may be useful in burns to prevent infections related to immune depression.

摘要

为了评估异丙肌苷对热损伤后免疫反应的影响,已进行了一系列实验。异丙肌苷治疗可显著刺激烧伤动物的细胞介导免疫反应。这一发现表明,异丙肌苷可能对烧伤有用,可预防与免疫抑制相关的感染。

相似文献

1
Immune response in thermally injured guinea-pigs treated with methisoprinol.用异丙肌苷治疗的热损伤豚鼠的免疫反应。
Int J Tissue React. 1984;6(2):123-6.
2
[Changes in laboratory and clinical parameters in subjects with chronic brucellosis treated with an immunomodulator: methisoprinol].[用免疫调节剂:异丙肌苷治疗的慢性布鲁氏菌病患者的实验室及临床参数变化]
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[Therapeutic experiences with the immunostimulator inosine pranobex].[免疫刺激剂异丙肌苷的治疗经验]
Fortschr Med. 1984 Oct 4;102(37):932-4.
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[Immunopotentiation with methisoprinol in patients with non-Hodgkin's lymphoma].
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Effect of isoprinosine on lymphocyte proliferation and natural killer cell activity following thermal injury.异丙肌苷对热损伤后淋巴细胞增殖及自然杀伤细胞活性的影响。
Immunopharmacol Immunotoxicol. 1989;11(4):631-44. doi: 10.3109/08923978909005391.
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A recent overview on in vitro and in vivo immunological activities of methisoprinol.美替沙腙体外和体内免疫活性的近期综述。
Allergol Immunopathol (Madr). 1982 Mar-Apr;10(2):109-14.
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[Effect of methisoprinol on postoperative immunodepression in subjects with malignant neoplasms].[美替沙腙对恶性肿瘤患者术后免疫抑制的影响]
Minerva Med. 1981 Mar 10;72(9):569-73.
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[Immunostimulative therapy of herpes zoster (three years' experience with inosiplex) (author's transl)].带状疱疹的免疫刺激疗法(三年使用肌苷片的经验)(作者译)
Z Hautkr. 1981 Nov 15;56(22):1457-66.
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[Effect of a treatment with methisoprinol on the frequency and duration of infectious respiratory and urinary episodes in the elderly].[异丙肌苷治疗对老年人传染性呼吸道和泌尿系统发作的频率及持续时间的影响]
Recenti Prog Med. 1984 Dec;75(12):1081-8.
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[Treatment of subacute sclerosing panencephalitis with methisoprinol. Considerations a propos of 3 cases].[用异丙肌苷治疗亚急性硬化性全脑炎。关于3例病例的思考]
Riv Neurobiol. 1981 Jul-Dec;27(34):621-5.

引用本文的文献

1
Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.异丙肌苷。对其药效学、药代动力学特性及治疗效果的初步综述。
Drugs. 1986 Nov;32(5):383-424. doi: 10.2165/00003495-198632050-00001.