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假性剥脱性疾病：与小带纤维亲和力的组织化学证据。

Pseudoexfoliative disease: histochemical evidence of an affinity with zonular fibres.

作者信息

Garner A, Alexander R A

出版信息

Br J Ophthalmol. 1984 Aug;68(8):574-80. doi: 10.1136/bjo.68.8.574.

DOI:10.1136/bjo.68.8.574
PMID:6204686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040415/
Abstract

The histochemical staining properties of the abnormal material deposited in the anterior segment of the eye in the pseudoexfoliation syndrome and the zonular ligaments of the lens are essentially the same. Both present the staining characteristics of oxytalan, the microfibrillar component of elastic tissue. Reasons are advanced for regarding the pseudoexfoliative material as a product of the ciliary and lenticular epithelium.

摘要

在假性剥脱综合征中，沉积于眼前节及晶状体悬韧带的异常物质的组织化学染色特性基本相同。二者均呈现弹力组织微原纤维成分——耐酸纤维的染色特征。文中提出了将假性剥脱物质视为睫状体和晶状体上皮产物的理由。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/52d3d9571372/brjopthal00152-0088-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/135830f0fa73/brjopthal00152-0085-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/c520f9b67ede/brjopthal00152-0085-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/9dbb2ab3de64/brjopthal00152-0086-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/9d8f17a2699d/brjopthal00152-0086-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/2c90ab5c6222/brjopthal00152-0086-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/ee22d7ea064e/brjopthal00152-0087-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/857459d51608/brjopthal00152-0087-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/536318e74598/brjopthal00152-0088-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/52d3d9571372/brjopthal00152-0088-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/135830f0fa73/brjopthal00152-0085-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/c520f9b67ede/brjopthal00152-0085-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/9dbb2ab3de64/brjopthal00152-0086-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/9d8f17a2699d/brjopthal00152-0086-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/2c90ab5c6222/brjopthal00152-0086-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/ee22d7ea064e/brjopthal00152-0087-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/857459d51608/brjopthal00152-0087-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/536318e74598/brjopthal00152-0088-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/1040415/52d3d9571372/brjopthal00152-0088-b.jpg

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Pseudoexfoliative disease: histochemical evidence of an affinity with zonular fibres.假性剥脱性疾病：与小带纤维亲和力的组织化学证据。
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引用本文的文献

1
Exfoliation syndrome and occludable angles.剥脱综合征与可闭角
Trans Am Ophthalmol Soc. 1994;92:845-944.
2
Galactose-containing glycoconjugates of the iris, the aqueous outflow passages and the cornea in capsular glaucoma. A lectin histochemical study.囊膜性青光眼患者虹膜、房水流出通道及角膜中含半乳糖的糖缀合物：凝集素组织化学研究
Graefes Arch Clin Exp Ophthalmol. 1995 Apr;233(4):192-9. doi: 10.1007/BF00183591.
3
Histochemistry of elastic and related fibres in the human eye in health and disease.

本文引用的文献

1
A clinical and pathologic study of exfoliation of the lens capsule.晶状体囊膜剥脱的临床与病理研究
Trans Am Ophthalmol Soc. 1957;55:189-212; discussion 212-6.
2
Tumours of the anterior uvea. III. Oxytalan fibres in the differential diagnosis of leiomyoma and malignant melanoma of the iris.前葡萄膜肿瘤。III. 弹力纤维在虹膜平滑肌瘤与恶性黑色素瘤鉴别诊断中的作用
Br J Ophthalmol. 1980 Nov;64(11):867-74. doi: 10.1136/bjo.64.11.867.
3
The protein composition of the ocular zonules.眼球悬韧带的蛋白质组成。
Histochem J. 1986 Aug;18(8):405-12. doi: 10.1007/BF01675332.
4
Pseudoexfoliative material contains an elastic microfibrillar-associated glycoprotein.假性剥脱物质含有一种弹性微原纤维相关糖蛋白。
Trans Am Ophthalmol Soc. 1986;84:304-20.
5
Immunogold localisation of laminin in normal and exfoliative iris.层粘连蛋白在正常及剥脱性虹膜中的免疫金定位
Br J Ophthalmol. 1990 Aug;74(8):450-7. doi: 10.1136/bjo.74.8.450.
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The cornea in exfoliation syndrome.
Doc Ophthalmol. 1992;80(4):329-33. doi: 10.1007/BF00154381.
Invest Ophthalmol Vis Sci. 1983 Jan;24(1):119-23.
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The ciliary body in senile exfoliation of the lens.
Can J Ophthalmol. 1973 Jul;8(3):394-403.
5
Accumulation of fibrillar protein in the aging human lens capsule, with special reference to the pathogenesis of pseudoexfoliative disease of the lens.衰老人晶状体囊膜中纤维状蛋白质的积聚，特别涉及晶状体假性剥脱性疾病的发病机制。
Arch Ophthalmol. 1969 Dec;82(6):815-21. doi: 10.1001/archopht.1969.00990020807016.
6
Oxytalan fibre formation in the cornea: a light and electron microscopical study.角膜中弹力纤维原纤维的形成：一项光镜和电镜研究。
Histopathology. 1977 May;1(3):189-99. doi: 10.1111/j.1365-2559.1977.tb01658.x.