Grunert G, Fernández S, Tchernitchin A N
Horm Res. 1984;19(4):253-62. doi: 10.1159/000179895.
Nongenomic responses to estrogen and the genomic responses in the different uterine cell types can be dissociated selectively. The present report describes morphometric methods for the evaluation of estrogen-induced uterine edema and of genomic responses in individual cell types. The morphometric measurements of the genomic responses correlated with a classically accepted biochemical method of genomic response evaluation in the uterus (increase in RNA/DNA). Edema correlated with the classically accepted method of evaluation of uterine water imbibition, i.e., estrogen-induced increase in uterine wet weight 6 h after hormone administration.
雌激素的非基因组反应与不同子宫细胞类型中的基因组反应可以被选择性地分离。本报告描述了用于评估雌激素诱导的子宫水肿以及个体细胞类型中基因组反应的形态计量学方法。基因组反应的形态计量学测量与子宫中基因组反应评估的一种经典认可的生化方法（RNA/DNA增加）相关。水肿与子宫吸水评估的经典认可方法相关，即激素给药6小时后雌激素诱导的子宫湿重增加。
