不同剂量儿茶酚雌激素对未成熟大鼠子宫嗜酸性粒细胞增多的影响。
Effect of various doses of catecholestrogens on uterine eosinophilia in the immature rat.
作者信息
Baumann P, Tchernitchin A N, Grunert G, Ball P
出版信息
Experientia. 1986 Feb 15;42(2):165-7. doi: 10.1007/BF01952449.
PMID:2419154
Abstract
This paper describes the induction of uterine eosinophilia as well as of deep endometrial edema and increase of uterine wet weight in the immature rat by the catecholestrogens 2-OH-estradiol and 4-OH-estradiol. These effects are thought to be mediated by eosinophils via a specific eosinophil receptor system. 4-OH-estradiol was equipotent with estradiol, whereas the effect of 2-OH-estradiol was significantly weaker.
摘要
本文描述了儿茶酚雌激素2-羟基雌二醇和4-羟基雌二醇可诱导未成熟大鼠子宫嗜酸性粒细胞增多、子宫内膜深层水肿以及子宫湿重增加。这些作用被认为是嗜酸性粒细胞通过特定的嗜酸性粒细胞受体系统介导的。4-羟基雌二醇与雌二醇的效力相当，而2-羟基雌二醇的作用则明显较弱。
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