Granados E N, Dawidzik J, O'Malley J, McGarry M, Bello J
J Interferon Res. 1984 Spring;4(2):155-60. doi: 10.1089/jir.1984.4.155.
We have prepared soluble complexes of poly ICL-CM dextran that are as effective interferon IFN inducers, in mice and in rhesus monkeys, as poly ICLC. Toxicity testing was carried out in mice and, poly ICL-CM dextran is less toxic, in mice, than poly ICLC is.
我们已经制备了聚ICL-CM葡聚糖的可溶性复合物，在小鼠和恒河猴中，其作为干扰素IFN诱导剂的效果与聚ICLC相同。在小鼠中进行了毒性测试，结果表明，在小鼠体内，聚ICL-CM葡聚糖的毒性低于聚ICLC。
