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[儿童膀胱横纹肌肉瘤:一例报告]

[Rhabdomyosarcoma of the bladder in a child: report of a case].

作者信息

Konami T, Ishida A, Arai Y, Takeuchi H, Takayama H, Tomoyoshi T

出版信息

Hinyokika Kiyo. 1984 Mar;30(3):387-95.

PMID:6205568
Abstract

A case of rhabdomyosarcoma of the urinary bladder in an 11-month-old boy is presented. The chief complaint was complete urinary retention and histological examination showed embryonal rhabdomyosarcoma of the bladder. Initially, he was treated with vincristine, actinomycin-D and radiation therapy. This therapy was not effective, and he was next treated with vincristine, bleomycin, and cis-DDP. This therapy was significantly effective, and the tumor became non-palpable on physical examination. After six courses he was discharged and maintenance chemotherapy was continued until the tumor relapsed 1 year later. Finally he died of dyspnea due to diffuse pulmonary metastases approximately 2 years after the first diagnosis. We herein discuss several points which affect the prognosis and the usefulness of chemotherapy, especially combination therapy with vincristine, bleomycin, and cis-DDP for recurrent cases.

摘要

本文报告了一例11个月大男孩的膀胱横纹肌肉瘤病例。主要症状为完全性尿潴留,组织学检查显示为膀胱胚胎性横纹肌肉瘤。最初,他接受了长春新碱、放线菌素-D和放射治疗。该治疗无效,随后他接受了长春新碱、博来霉素和顺铂治疗。该治疗显著有效,体格检查时肿瘤已无法触及。六个疗程后他出院,继续进行维持化疗,直到1年后肿瘤复发。最终,在首次诊断约2年后,他因弥漫性肺转移导致呼吸困难而死亡。我们在此讨论了影响预后的几个要点以及化疗的有效性,特别是长春新碱、博来霉素和顺铂联合治疗复发病例的有效性。

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