Tatsuta M, Iishi H, Okuda S, Taniguchi H
Endoscopy. 1984 Jul;16(4):131-4. doi: 10.1055/s-2007-1018556.
The clinicopathological features of the early gastric cancers in the upper part of the stomach, and the accuracy of their diagnosis by routine endoscopic examination were examined, and the accuracy of diagnosis of minute and flat cancers in the upper portion of the stomach by routine endoscopic examination and by the endoscopic Congo red-methylene blue test developed in our clinic were compared. Early cancers in the upper part of the stomach occurred in the elderly patient, and grossly elevated types were frequent. Endoscopically they were most difficult to diagnose by a single routine endoscopic examination, because they were frequently overlooked, and adequate biopsy was difficult in some cases. A correct diagnosis of minute and flat cancers in the upper part of the stomach by routine examination was made in only 27.3% and 25.0% of the cases, respectively. But with the Congo red-methylene blue test the diagnostic rate was raised significantly to 75.0% and 83.3%, respectively. In this test, Congo red and methylene blue sprayed on the surface of the tumor were bleached white 2 to 5 minutes after application, in sharp contrast to the unaffected mucosa.
对胃上部早期胃癌的临床病理特征及其通过常规内镜检查的诊断准确性进行了研究，并比较了常规内镜检查与我院研发的内镜刚果红 - 亚甲蓝试验对胃上部微小癌和平坦癌的诊断准确性。胃上部的早期癌症多见于老年患者，且隆起型较为常见。在内镜下，仅通过一次常规内镜检查很难诊断这些癌症，因为它们经常被忽视，而且在某些情况下难以进行充分活检。常规检查对胃上部微小癌和平坦癌的正确诊断率分别仅为27.3%和25.0%。但采用刚果红 - 亚甲蓝试验后，诊断率分别显著提高至75.0%和83.3%。在该试验中，喷洒在肿瘤表面的刚果红和亚甲蓝在应用后2至5分钟变白，与未受影响的黏膜形成鲜明对比。
