Olive D, Dubreuil P, Mawas C
Immunogenetics. 1984;20(3):253-64. doi: 10.1007/BF00364207.
Monoclonal antibodies reacting with TL-like class I antigens expressed on the surface of human thymocytes and some T leukemia lines were found to define three independent epitopic clusters, two of which could be shown to reside on serologically distinct molecular subsets by a solid-phase radioimmunoassay as well as by sequential immunoprecipitation. Both molecular subsets consist of a 49-K heavy chain associated with a beta-2 microglobulin light chain. Thymocytes expressed similar amounts of the two molecular subsets, while on T leukemia lines the amount of these two molecular subsets varied from line to line.
发现与人类胸腺细胞和一些T白血病细胞系表面表达的TL样I类抗原发生反应的单克隆抗体可定义三个独立的表位簇，其中两个表位簇可通过固相放射免疫测定以及连续免疫沉淀法显示位于血清学上不同的分子亚群上。这两个分子亚群均由与β2微球蛋白轻链相关的49-K重链组成。胸腺细胞表达的这两个分子亚群数量相似，而在T白血病细胞系中，这两个分子亚群的数量因细胞系而异。
