Holbro P, Dalquen P, Perruchoud A, Herzog H
Dtsch Med Wochenschr. 1978 Jan 6;103(1):17-20. doi: 10.1055/s-0028-1104373.
The accuracy of different histological and cytological methods were analysed in 240 patients with primary lung cancer. The diagnosis had been confirmed by either biopsy, surgery or autopsy. Using multiple diagnostic procedures a positive pre-operative diagnosis was obtained in 86.5%. Where the tumour was endoscopically visible and accessible to direct biopsy the correct diagnosis was made in 97.5%. In case of more peripheral tumour localisation positive results were obtained by cytological tests in 76.5%. The most accurate method of diagnosis was direct forceps biopsy of visible tumours (91% positive). Bronchial washing was positive in 64%, post-bronchoscopic sputum analysis in 60%, pre-bronchoscopic sputum in 55% and bronchial brushing in 30%.
对240例原发性肺癌患者不同组织学和细胞学方法的准确性进行了分析。诊断通过活检、手术或尸检得以证实。采用多种诊断程序，术前阳性诊断率为86.5%。在内镜可见且可直接活检的肿瘤中，正确诊断率为97.5%。对于肿瘤定位更外周的情况，细胞学检查的阳性率为76.5%。最准确的诊断方法是对可见肿瘤进行直接钳取活检（阳性率91%）。支气管冲洗阳性率为64%，支气管镜检查后痰液分析阳性率为60%，支气管镜检查前痰液阳性率为55%，支气管刷检阳性率为30%。
