Kirchhoff H, Heitmann J, Dubenkropp H, Schmidt R
Vet Microbiol. 1984 Jul;9(3):237-48. doi: 10.1016/0378-1135(84)90041-5.
An antigenic relationship between Mycoplasma arthritidis and rat tissues could be demonstrated using the enzyme-immune assay and the agar gel double diffusion test. Cross-reactions were observed with joint homogenates as well as with muscle, lung, liver, kidney, spleen and brain tissue from rats. In addition, antibodies against joint homogenate were found in the sera of rats infected with M. arthritidis ISR 1 using the indirect hemagglutination test. The significance of common antigens between M. arthritidis and rat tissues for the pathogenesis of the M. arthritidis polyarthritis in rats is discussed.
利用酶免疫测定法和琼脂凝胶双向扩散试验可证明关节炎支原体与大鼠组织之间存在抗原关系。在大鼠的关节匀浆以及肌肉、肺、肝、肾、脾和脑组织中均观察到交叉反应。此外，使用间接血凝试验在感染关节炎支原体ISR 1的大鼠血清中发现了针对关节匀浆的抗体。本文讨论了关节炎支原体与大鼠组织之间的共同抗原对大鼠关节炎支原体多关节炎发病机制的意义。
