Fontaine G, Cansell A, Lechat P, Pavie A, Grosgogeat Y
Pacing Clin Electrophysiol. 1984 Nov;7(6 Pt 2):1351-6. doi: 10.1111/j.1540-8159.1984.tb05707.x.
Defibrillation thresholds are studied in normal dog hearts after induction of ventricular fibrillation by alternating current. Shocks of progressively increasing energies are tried after a period of 10 seconds of sustained ventricular fibrillation. The endocardial electrode system may be either unipolar or bipolar, the distal electrode being situated at the right ventricular apex. The results suggest that for an optimal capacitor in the range of 9-20 uF, unipolar shocks are more effective than bipolar shocks (3-10 versus 10-30 Joules). In addition, several cardiac arrhythmias, including rapid ventricular tachycardia, accelerated idioventricular rhythm, and transient AV block are frequently observed. We conclude that (1) an implantable unipolar endocardial defibrillator seems feasible; and (2) the design should include the appropriate circuits to treat the arrhythmias observed after the shocks.
通过交流电诱发心室颤动后，对正常犬心脏的除颤阈值进行了研究。在持续心室颤动10秒后，尝试使用能量逐渐增加的电击。心内膜电极系统可以是单极的或双极的，远端电极位于右心室尖部。结果表明，对于9 - 20微法范围内的最佳电容器，单极电击比双极电击更有效（3 - 10焦耳对10 - 30焦耳）。此外，还经常观察到几种心律失常，包括快速室性心动过速、加速性室性自主心律和短暂性房室传导阻滞。我们得出结论：（1）植入式单极心内膜除颤器似乎是可行的；（2）设计应包括适当的电路来治疗电击后观察到的心律失常。
