Dawson W O
Intervirology. 1978;9(5):295-303. doi: 10.1159/000148947.
Incubation of tobacco mosaic virus (TMV)-infected tissue at 40 degrees for 12 h destroyed the capacity for TMV RNA replication. Upon shift of the tissue from 40 to 25 degrees, synthesis of TMV RNA did not resume. Incubation at 40 degrees for 1 h did not destory the TMV RNA replicase, because viral RNA synthesis resumed upon return to 25 degrees. However, upon further incubation at 25 degrees, the synthesis rate of TMV RNA gradually declined. Upon still further incubation at 25 degrees (16-20 h), the synthesis of TMV RNA in tissue incubated at 40 degrees for either 1 or 12 h recovered. This recovery was inhibited by cycloheximide but not by 2-thiouracil.
将感染烟草花叶病毒（TMV）的组织在40摄氏度下孵育12小时会破坏TMV RNA复制的能力。当组织从40摄氏度转移到25摄氏度时，TMV RNA的合成不会恢复。在40摄氏度下孵育1小时不会破坏TMV RNA复制酶，因为回到25摄氏度后病毒RNA合成会恢复。然而，在25摄氏度下进一步孵育时，TMV RNA的合成速率逐渐下降。在25摄氏度下进一步孵育（16 - 20小时）后，在40摄氏度下孵育1小时或12小时的组织中TMV RNA的合成恢复了。这种恢复受到环己酰亚胺的抑制，但不受2 - 硫尿嘧啶的抑制。
