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[局部抗菌治疗:氯碘羟喹和三溴酚铋-氧化锌制剂的疗效]

[Topical antimicrobial therapy: the efficacy of clioquinol- and tribromphenolbismuth- zinc oxide preparations].

作者信息

Kaiser H J, Kunze J

出版信息

Fortschr Med. 1982 Jul 8;100(26):1265-7.

PMID:6214486
Abstract

Clioquinol- and tribromphenolwismut zinc oxide preparations were tested in vitro in order to investigate their bactericidal and bacteriostatic efficacy against strains of staphylococcus aureus, E. coli, pseudomonas as well as against the fungi candida albicans and trichophyton rubrum. The results show that there was both a bacteriostatic and a bacteriocidal effect of clioquinol except against pseudomonas. Tribromphenolwismut has less efficacy. In spite of some suggestions in the literature our results confirm that the efficacy of clioquinol is not impaired if combined with zinc oxide. The use of this well tolerated preparation is recommended in the treatment of infectious dermatoses even today.

摘要

对氯碘喹啉和三溴酚铋氧化锌制剂进行了体外测试,以研究它们对金黄色葡萄球菌、大肠杆菌、假单胞菌菌株以及白色念珠菌和红色毛癣菌等真菌的杀菌和抑菌效果。结果表明,除了对假单胞菌外,对氯碘喹啉具有抑菌和杀菌作用。三溴酚铋的效果较差。尽管文献中有一些建议,但我们的结果证实,对氯碘喹啉与氧化锌联合使用时其效果不会受到影响。即使在今天,仍推荐使用这种耐受性良好的制剂来治疗感染性皮肤病。

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1
[Topical antimicrobial therapy: the efficacy of clioquinol- and tribromphenolbismuth- zinc oxide preparations].[局部抗菌治疗:氯碘羟喹和三溴酚铋-氧化锌制剂的疗效]
Fortschr Med. 1982 Jul 8;100(26):1265-7.
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