Arsenescu G, Sabău M, Tintoiu I, Meclea G, Popa A
Med Interne. 1982 Jan-Mar;20(1):33-8.
The effect of age on the maximal spatial QRS vector (MSQRSV) in the Frank lead system was correlated with th posterior left ventricular wall thickness (PLVWT), the interventricular septum thickness (IVST) determined by echocardiography, and with blood pressure in 300 normal men, distributed by age groups (20-29, 30-39, 40-60). With advancing age, a significant decrease of MSQRSV accompanied by a significant increase of PLVWT was observed while the increase of IVST and of blood pressures with age were found non significant. It was concluded that: 1. blood pressure is not the sole determinant of hypertrophy; 2. myocardial hypertrophy is not the sole determinant of cardiac voltage increase; 3. there is some degree of myocardial sclerosis in healthy people aged over 40-60 years; 4. in left ventricular hypertrophy the left ventricular muscular mass cannot be accurately predicted from the heart electrical phenomena; 5. the results obtained were in agreement with those of authors describing different aspects of normal Frank ECG and vectorcardiogram (VCG) in subjects under and over 40-50 years of age; 6. the variability of the degree of age influence on normal ECG from one country to another could explain the different diagnostic criteria for the same cardiac disease in computerized programs.
在Frank导联系统中，年龄对最大空间QRS向量（MSQRSV）的影响与300名按年龄组（20 - 29岁、30 - 39岁、40 - 60岁）分布的正常男性的左心室后壁厚度（PLVWT）、经超声心动图测定的室间隔厚度（IVST）以及血压相关。随着年龄的增长，观察到MSQRSV显著降低，同时PLVWT显著增加，而IVST和血压随年龄的增加无显著变化。得出以下结论：1. 血压不是肥大的唯一决定因素；2. 心肌肥大不是心脏电压升高的唯一决定因素；3. 40 - 60岁以上的健康人存在一定程度的心肌硬化；4. 在左心室肥大中，无法从心脏电现象准确预测左心室肌肉质量；5. 所得结果与描述40 - 50岁上下受试者正常Frank心电图和向量心电图（VCG）不同方面的作者的结果一致；6. 不同国家年龄对正常心电图影响程度的差异可以解释计算机程序中相同心脏疾病的不同诊断标准。
