Johnstone E C, Crow T J, Frith C D, Husband J, Kreel L
Lancet. 1976 Oct 30;2(7992):924-6. doi: 10.1016/s0140-6736(76)90890-4.
By comparison with age-matched controls in employment, 17 institutionalised schizophrenic patients were shown by computerised axial tomography of the brain to have increased cerebral ventricular size. Within the group of schizophrenic patients increased ventricular size was highly significantly related to indices of cognitive impairment.
