人血浆中保泰松的葡萄糖醛酸苷测定
GLC determination of phenylbutazone in human plasma.
作者信息
Sioufi A, Caudal F, Marfil F
出版信息
J Pharm Sci. 1978 Feb;67(2):243-5. doi: 10.1002/jps.2600670230.
PMID:621647
Abstract
A GLC method for phenylbutazone at concentrations down to 10 ng/ml in human plasma is described. After addition of an internal standard, phenylbutazone is extracted at pH 5 into benzene. The dry extract is dissolved in benzene, and phenylbutazone is determined by GLC using a 63Ni-electron-capture detector.
摘要
本文描述了一种用于测定人血浆中浓度低至10纳克/毫升的保泰松的气相色谱法。加入内标后，在pH 5条件下将保泰松萃取到苯中。干燥提取物溶于苯中，使用63Ni电子捕获检测器通过气相色谱法测定保泰松。
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