多形核中性粒细胞表达常见的急性淋巴细胞白血病抗原。
Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen.
作者信息
Cossman J, Neckers L M, Leonard W J, Greene W C
出版信息
J Exp Med. 1983 Mar 1;157(3):1064-9. doi: 10.1084/jem.157.3.1064.
Abstract
Monoclonal antibodies J5, VIL-A1, and BA-3, known to react with the common acute lymphoblastic leukemia antigen (CALLA) were found to specifically stain normal human polymorphonuclear neutrophils (PMN). The antigen detected on PMN had a molecular weight (95,000-110,000 mol wt) close to that of CALLA (95,000-100,000 mol wt) and thus these surface membrane antigens are likely related, if not identical. The fluorescent staining intensity of PMN is comparable to that of CALLA-positive leukemic cells and the presence of PMN in patient samples could potentially produce false-positive results in diagnosis.
摘要
已知可与常见急性淋巴细胞白血病抗原（CALLA）发生反应的单克隆抗体J5、VIL-A1和BA-3，被发现可特异性地对正常人多形核中性粒细胞（PMN）进行染色。在PMN上检测到的抗原分子量（95,000 - 110,000道尔顿）与CALLA的分子量（95,000 - 100,000道尔顿）相近，因此，即使这些表面膜抗原不完全相同，它们也可能相关。PMN的荧光染色强度与CALLA阳性白血病细胞的染色强度相当，患者样本中PMN的存在可能会在诊断中产生假阳性结果。
相似文献
1
Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen.多形核中性粒细胞表达常见的急性淋巴细胞白血病抗原。
J Exp Med. 1983 Mar 1;157(3):1064-9. doi: 10.1084/jem.157.3.1064.
2
Different reactivity of monoclonal antibodies against common acute lymphoblastic leukaemia antigen (CD10).针对常见急性淋巴细胞白血病抗原（CD10）的单克隆抗体的不同反应性。
J Clin Pathol. 1987 May;40(5):490-3. doi: 10.1136/jcp.40.5.490.
3
Difference between monoclonal antibodies against the common acute leukemia antigen from two different hybridomas.来自两种不同杂交瘤的抗普通急性白血病抗原单克隆抗体之间的差异。
Anticancer Res. 1983 Nov-Dec;3(6):407-8.
4
Bone marrow macrophages and megakaryocytes express common acute lymphoblastic leukaemia antigen.
Leuk Res. 1985;9(9):1155-9. doi: 10.1016/0145-2126(85)90106-7.
5
Distribution and modulation of a human leukemia-associated antigen (CALLA).一种人类白血病相关抗原（CALLA）的分布与调节
J Immunol. 1983 Oct;131(4):2038-45.
6
7
Monoclonal antibodies to CALLA do not alter polymorphonuclear functions.针对CALLA的单克隆抗体不会改变多形核白细胞的功能。
Am J Hematol. 1986 Nov;23(3):209-15. doi: 10.1002/ajh.2830230304.
8
Unique epitopes of common acute lymphoblastic leukemia antigen detected by new monoclonal antibodies.新型单克隆抗体检测到的常见急性淋巴细胞白血病抗原的独特表位
Cancer Res. 1987 Apr 15;47(8):2160-6.
9
Discrepancy between flow cytometric analyses of CALLA using two monoclonal antibodies.使用两种单克隆抗体对CALLA进行流式细胞术分析时的差异。
Exp Cell Biol. 1987;55(6):322-30. doi: 10.1159/000163435.
10
Immunocytological and immunochemical analysis on the common acute lymphoblastic leukemia antigen (CALLA): evidence that CALLA on ALL cells and granulocytes are structurally related.
Hybridoma. 1988 Jun;7(3):227-36. doi: 10.1089/hyb.1988.7.227.
引用本文的文献
1
Exploratory Study of CD10 Polymorphonuclear Leukocytes Preceding and Correlating With Postsurgical Inflammation.CD10多形核白细胞在术后炎症之前出现及与之相关的探索性研究。
Scand J Immunol. 2025 Jul;102(1):e70042. doi: 10.1111/sji.70042.
2
Immunoregulatory functions of mature CD10 and immature CD10 neutrophils in sepsis patients.脓毒症患者中成熟CD10和未成熟CD10中性粒细胞的免疫调节功能
Front Med (Lausanne). 2023 Jan 4;9:1100756. doi: 10.3389/fmed.2022.1100756. eCollection 2022.
3
Neutrophil and Eosinophil Responses Remain Abnormal for Several Months in Primary Care Patients With COVID-19 Disease.新冠病毒疾病初级护理患者的中性粒细胞和嗜酸性粒细胞反应在数月内仍不正常。
Front Allergy. 2022 Jul 27;3:942699. doi: 10.3389/falgy.2022.942699. eCollection 2022.
4
The extracellular sialidase NEU3 primes neutrophils.细胞外唾液酸酶 NEU3 可激活中性粒细胞。
J Leukoc Biol. 2022 Dec;112(6):1399-1411. doi: 10.1002/JLB.3A0422-217RR. Epub 2022 Jul 28.
5
A subset of low density granulocytes is associated with vascular calcification in chronic kidney disease patients.一组低浓度的嗜中性粒细胞与慢性肾病患者的血管钙化有关。
Sci Rep. 2019 Sep 13;9(1):13230. doi: 10.1038/s41598-019-49429-x.
6
High FLT3 expression and IL10 (G1082A) polymorphism in poor overall survival in calla acute lymphoblastic leukemia.高 FLT3 表达和 IL10（G1082A）多态性与 Call-急性淋巴细胞白血病患者总体生存不良相关。
Mol Biol Rep. 2013 Feb;40(2):1609-13. doi: 10.1007/s11033-012-2209-4. Epub 2012 Oct 20.
7
A new method for high speed, sensitive detection of minimal residual disease.一种用于高速、灵敏检测微小残留病的新方法。
Cytometry A. 2012 Feb;81(2):169-75. doi: 10.1002/cyto.a.21124. Epub 2011 Sep 13.
8
Identification of human neutrophils during experimentally induced inflammation in mice with transplanted CD34+ cells from human umbilical cord blood.在移植了来自人脐带血的CD34+细胞的小鼠实验性诱导炎症过程中对人中性粒细胞的鉴定。
Int J Hematol. 2006 Oct;84(3):231-7. doi: 10.1532/IJH97.06040.
9
Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients.
Rheumatol Int. 2005 Jun;25(5):336-40. doi: 10.1007/s00296-004-0447-z. Epub 2004 Mar 3.
10
Flow cytometric study of neutrophilic granulopoiesis in normal bone marrow using an expanded panel of antibodies: correlation with morphologic assessments.使用扩展抗体组合对正常骨髓中性粒细胞生成进行流式细胞术研究：与形态学评估的相关性
J Clin Lab Anal. 2004;18(1):36-41. doi: 10.1002/jcla.20001.
本文引用的文献
1
2
Simple and rapid measurement of human T lymphocytes and their subclasses in peripheral blood.外周血中人类T淋巴细胞及其亚群的简单快速检测
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4914-7. doi: 10.1073/pnas.77.8.4914.
3
Analysis of human leukemia/lymphoma cell lines with monoclonal antibodies BA-1, BA-2 and BA-3.使用单克隆抗体BA-1、BA-2和BA-3对人白血病/淋巴瘤细胞系进行分析。
Leuk Res. 1982;6(3):299-305. doi: 10.1016/0145-2126(82)90091-1.
4
5
Distribution of common acute lymphoblastic leukemia antigen in nonhematopoietic tissues.常见急性淋巴细胞白血病抗原在非造血组织中的分布。
J Exp Med. 1981 Oct 1;154(4):1249-54. doi: 10.1084/jem.154.4.1249.
6
7
A monoclonal antibody to human acute lymphoblastic leukaemia antigen.一种针对人类急性淋巴细胞白血病抗原的单克隆抗体。
Nature. 1980 Feb 7;283(5747):583-5. doi: 10.1038/283583a0.
8
A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.一种似乎能识别人类T细胞生长因子受体的单克隆抗体；该受体的部分特性
Nature. 1982 Nov 18;300(5889):267-9. doi: 10.1038/300267a0.
9
Serotherapy of acute lymphoblastic leukemia with monoclonal antibody.单克隆抗体治疗急性淋巴细胞白血病的血清疗法
Blood. 1981 Jul;58(1):141-52.
10
VIL-A1, a monoclonal antibody reactive with common acute lymphatic leukemia cells.VIL-A1，一种与常见急性淋巴细胞白血病细胞发生反应的单克隆抗体。
Leuk Res. 1982;6(2):137-47. doi: 10.1016/0145-2126(82)90019-4.
Zotero 插件