Csanády M, Gáspár L, Hogye M, Gruber N
Int J Cardiol. 1983;2(3-4):349-61. doi: 10.1016/0167-5273(83)90006-2.
We used echocardiography to study anatomic and functional changes of the heart in 25 patients with acromegaly. Asymmetric septal hypertrophy was found in 10 patients, in the range of 12 to 30 mm, with an average of 16 mm. The degree of septum-thickness was severe in 1 case, marked in 5 cases and mild in 4 cases. Concentric left ventricular hypertrophy was present in 1 patient. In 8 patients the left ventricle was normal and left ventricular dilatation of more than 60 mm was present in 6 cases. Except in one patient, the ejection fraction was decreased in the dilated group, indicating diminished myocardial contractility. The growth hormone level was higher in patients with left ventricular hypertrophy as compared to those patients with normal or dilated left ventricles. In acromegaly primary myocardial hypertrophy may be related to the growth hormone level.
我们采用超声心动图研究了25例肢端肥大症患者心脏的解剖和功能变化。10例患者出现不对称性室间隔肥厚，范围为12至30毫米，平均为16毫米。室间隔增厚程度重度1例，中度5例，轻度4例。1例患者出现同心性左心室肥厚。8例患者左心室正常，6例患者左心室扩张超过60毫米。除1例患者外，扩张组射血分数降低，提示心肌收缩力减弱。与左心室正常或扩张的患者相比，左心室肥厚患者的生长激素水平更高。在肢端肥大症中，原发性心肌肥厚可能与生长激素水平有关。
