Wolfe W G, Oldham H N, Rankin J S, Moran J F
Ann Surg. 1983 Jun;197(6):738-42. doi: 10.1097/00000658-198306000-00013.
Since adopting a policy of immediate operation on patients with acute dissection of the ascending aorta, 42 men and 6 women (ages 18-67 years) have been managed surgically. Thirty-two patients had graft replacement of the ascending aorta and resuspension of the incompetent aortic valve. One of these had a coronary graft. There were five deaths in this group. Eight patients required aortic valve replacement because of a diseased aortic valve as well as grafting of the ascending aorta, with one death. Three patients had resuspension of the aortic valve and primary repair of their dissection without mortality. Two patients were managed successfully with an intraluminal prosthesis and resuspension of the aortic valve. Another patient had successful repair with a valved conduit and reimplantation of the coronaries. Two patients dissected 4 and 6 years after aortic valve replacement and neither survived operative repair. Of the surviving patients, one required dialysis, one a femoral-femoral bypass graft, and one an axillo-femoral bypass graft. One patient required a pacemaker for heart block, and two underwent successful repair of suture line aneurysms, both occurring three years after operation. On the basis of this experience, prompt surgical intervention for acute ascending aortic dissection is the treatment of choice. A variety of techniques are available to repair the dissected aorta. Long-term results for resuspension of the aortic valve in acute ascending aortic dissection have been excellent and emphasize that valve replacement should be reserved for those patients found at operation to have a primary abnormality of the aortic valve.
自从对升主动脉急性夹层患者采取立即手术的政策以来,已对42名男性和6名女性(年龄18 - 67岁)进行了手术治疗。32例患者进行了升主动脉移植置换及功能不全主动脉瓣的再悬吊术。其中1例进行了冠状动脉移植。该组有5例死亡。8例患者因主动脉瓣病变以及升主动脉移植而需要进行主动脉瓣置换,其中1例死亡。3例患者进行了主动脉瓣再悬吊术及夹层的一期修复,无死亡病例。2例患者通过腔内假体及主动脉瓣再悬吊术成功治疗。另1例患者通过带瓣管道及冠状动脉再植入成功修复。2例患者在主动脉瓣置换术后4年和6年发生夹层,均未在手术修复后存活。在存活患者中,1例需要透析,1例需要股-股旁路移植,1例需要腋-股旁路移植。1例患者因心脏传导阻滞需要起搏器,2例患者成功修复了缝线处动脉瘤,均发生在术后3年。基于这一经验,对升主动脉急性夹层进行及时的手术干预是首选治疗方法。有多种技术可用于修复夹层主动脉。急性升主动脉夹层中主动脉瓣再悬吊术的长期效果极佳,并强调瓣膜置换应仅用于那些在手术中发现有主动脉瓣原发性异常的患者。