抗变形链球菌6715葡糖基转移酶单克隆抗体的制备
Production of monoclonal antibody against a glucosyltransferase of Streptococcus mutans 6715.
作者信息
Furuta T, Nisizawa T, Chiba J, Hamada S
出版信息
Infect Immun. 1983 Aug;41(2):872-5. doi: 10.1128/iai.41.2.872-875.1983.
Abstract
A mouse hybrid cell line secreted monoclonal antibody which reacted specifically with Streptococcus mutans 6715 (serotype g) glucosyltransferase (GTase)-synthesizing water-insoluble glucan and inhibited with enzyme reaction. The antibody was cross-reactive with GTase of serotype d but not with GTase of other serotypes of S. mutans when an enzyme-linked immunosorbent assay was used.
摘要
一种小鼠杂交细胞系分泌的单克隆抗体，可与变形链球菌6715（血清型g）葡糖基转移酶（GTase）特异性反应，该酶可合成水不溶性葡聚糖并抑制酶反应。当使用酶联免疫吸附测定时，该抗体与血清型d的GTase有交叉反应，但与变形链球菌其他血清型的GTase无交叉反应。
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