Clark R P
J Clin Pathol. 1983 Aug;36(8):839-46. doi: 10.1136/jcp.36.8.839.
Toxic effects of formaldehyde in humans are discussed in relation to occupational exposure and tolerance to this agent. Carcinogenic and mutagenic properties of formaldehyde have been reported in animals and this has led to concern about a possible role in human cancer. The current state of affairs is reviewed in the light of a lack of direct evidence linking formaldehyde with cancer in man and in relation to recommended exposure levels. It is important to employ effective means of containment and practical methods for reducing exposure to formaldehyde in pathology departments and post-mortem rooms are described.
本文讨论了甲醛对人体的毒性作用,涉及职业暴露以及人体对该物质的耐受性。甲醛在动物身上已被报道具有致癌和致突变特性,这引发了人们对其在人类癌症中可能作用的担忧。鉴于缺乏将甲醛与人类癌症直接联系起来的证据以及推荐的暴露水平,本文对当前状况进行了综述。在病理科和验尸房采用有效的控制手段和实用方法来减少甲醛暴露非常重要,本文对此进行了描述。