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糖尿病母亲所生婴儿的超声心动图特征

Echocardiographic profile of infants of diabetic mothers.

作者信息

Trowitzsch E, Bigalke U, Gisbertz R, Kallfelz H C

出版信息

Eur J Pediatr. 1983 Sep;140(4):311-5. doi: 10.1007/BF00442671.

DOI:10.1007/BF00442671
PMID:6226528
Abstract

Echocardiographic M-mode examinations were performed in 30 infants of diabetic mothers (IDM). Twelve of them had severe symptoms with hyperbilirubinemia, respiratory distress syndrome, septicemia and hypoglycemia in the neonatal period. The gestational age ranged from the 34th week to the 40th week, the birth weight ranging between 2280 g and 5820 g (mean 3455 g). Fifteen patients were restudied at different ages. In group A (age 1-14 days) out of 23, in group B (age 14 days-6 months) 5 from 13 IDM and in group C (older than 6 months, (n=10) no IDM had an increased ratio of intraventricular septal thickness (IVS) to left ventricular posterior wall thickness (LVPW). One patient showed a systolic anterior motion of the mitral valve (SAM) without having other symptoms for a left ventricular outflow tract obstruction. All measured dimensions normalized within 6 months. It is concluded that a form of prematurity may be responsible for the transient, asymmetrical, septal hypertrophy.

摘要

对30名患有糖尿病母亲的婴儿(IDM)进行了超声心动图M型检查。其中12名在新生儿期出现严重症状,伴有高胆红素血症、呼吸窘迫综合征、败血症和低血糖。胎龄从第34周到第40周不等,出生体重在2280克至5820克之间(平均3455克)。15名患者在不同年龄段进行了复查。在A组(1至14天龄)的23名IDM中,B组(14天至6个月龄)的13名IDM中有5名,C组(6个月以上,n = 10)的IDM中没有室间隔厚度(IVS)与左心室后壁厚度(LVPW)的比值增加。1名患者出现二尖瓣收缩期前向运动(SAM),但没有左心室流出道梗阻的其他症状。所有测量尺寸在6个月内恢复正常。结论是,一种早产形式可能是短暂性、不对称性间隔肥厚的原因。

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Pediatr Res. 2018 Jul;84(Suppl 1):78-88. doi: 10.1038/s41390-018-0075-z.
2
Markers of maternal and infant metabolism are associated with ventricular dysfunction in infants of obese women with type 2 diabetes.标志物母体和婴儿代谢与肥胖 2 型糖尿病妇女的婴儿心室功能障碍有关。
Pediatr Res. 2017 Nov;82(5):768-775. doi: 10.1038/pr.2017.140. Epub 2017 Jun 28.

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