Sikuler E, Dvilansky A, Skibin A, Quastel M R
Vox Sang. 1978;34(1):25-31. doi: 10.1111/j.1423-0410.1978.tb02876.x.
Until recently, hepatitis type B was thought to be transmitted parenterally. However, much evidence has appeared regarding non-parenteral transmission. Hospital personnel are exposed both ways to this disease. We compared the incidence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs) among 388 workers at a major medical center in Israel with 203 kibbutz residents, using radioimmunoassay procedures. Of the hospital personnel, 1.8% were found to carry the antigen and 23.9% the antibody. In contrast, 0.5% of kibbutz personnel were antigen-positive and 11.8% carried the antibody. The highest incidence of antibody was found among people born in middle-eastern countries outside of Israel. These results show a significant increase in the exposure of hospital personnel to hepatitis B virus. A marked increase in the frequency of sera positive for anti-HBs occurred after the first year of hospital work.
直到最近,乙型肝炎还被认为是通过非肠道途径传播的。然而,现在已经出现了许多关于非非肠道传播的证据。医院工作人员通过这两种途径接触这种疾病。我们采用放射免疫测定法,比较了以色列一家大型医疗中心的388名工作人员与203名基布兹居民中乙型肝炎表面抗原(HBsAg)和抗体(抗-HBs)的发生率。在医院工作人员中,发现1.8%的人携带抗原,23.9%的人携带抗体。相比之下,基布兹人员中0.5%的人抗原呈阳性,11.8%的人携带抗体。抗体发生率最高的是出生在以色列以外中东国家的人。这些结果表明医院工作人员接触乙型肝炎病毒的情况显著增加。在医院工作的第一年之后,抗-HBs血清阳性频率显著增加。