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[采用放射免疫法鉴定的抗乙肝表面抗原抗体]

[Antibodies against HBs antigens as identified using the radioimmunologic method].

作者信息

Hocevar M, Glonar L

出版信息

Bilt Hematol Transfuz. 1977;5(1):59-67.

PMID:921732
Abstract

Antibodies to hepatitis Bs antigen identified only by radioimmunoassay, which is 8000 times more sensitive than counterelectrophoresis, were found in blood donors in 17%, in the Haemodialysis centre in 44%, in the patients of this centre in 47%. HBsAg and the antibodies have been tested in different series of albumin and gammaglobulin. Immunoglobulin anti HBs was prepared by the Blood transfusion centre in Ljubljana, and the Imunoloski zavod in Zagreb, and the problem of prevention, and production is discussed. Antigen-antibody complexes were prepared in vitro, and the results of the respective tests described.

摘要

仅通过放射免疫测定法鉴定出的乙肝表面抗原抗体,其灵敏度比对流电泳高8000倍,在17%的献血者、44%的血液透析中心患者以及该中心47%的患者血液中被发现。乙肝表面抗原和抗体已在不同系列的白蛋白和丙种球蛋白中进行了检测。卢布尔雅那的输血中心和萨格勒布的免疫研究所制备了抗乙肝免疫球蛋白,并讨论了预防和生产问题。体外制备了抗原-抗体复合物,并描述了各自的检测结果。

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