Boccalon H, Venerandi M C, Lozes A, Puel P
J Mal Vasc. 1984;9(1):11-6.
The microcirculatory unit, which links arterioles with venules, is responsible for metabolic exchanges with the interstitial tissues and for the regulation of skin temperature. The sympathetic system controls cutaneous vascularization. A satisfactory method for dynamic clinical investigation of skin vascularization, previously not available, is now possible with the Doppler laser flowmeter which provides relative measurement of blood flow in the microcirculation. Three studies were conducted using this simple technique. Changes in skin blood flow were recorded in healthy volunteers during physiological stress: reactive hyperemia, hot and cold reaction test, respiratory changes, postural modifications. In patients with arteritis, the immediate effects of lumbar sympathectomy on skin blood flow were measured. During exploration of patients with vasomotor disorders, the cold test was performed by exposing the extremities in a thermal chamber: laser flowmeter recordings provided data on specific alterations occurring during a disease or Raynaud's syndrome. These findings will assist quantification of, and the application of predictive tests to the most useful measures to adopt for vasomotor disorders.
微循环单元连接小动脉和小静脉，负责与间质组织进行代谢交换并调节皮肤温度。交感神经系统控制皮肤血管形成。以前无法实现的用于皮肤血管形成动态临床研究的令人满意的方法，现在借助能提供微循环中血流相对测量值的多普勒激光流量计成为可能。使用这种简单技术进行了三项研究。在生理应激期间记录了健康志愿者皮肤血流的变化：反应性充血、热冷反应试验、呼吸变化、体位改变。在动脉炎患者中，测量了腰交感神经切除术对皮肤血流的即时影响。在对血管舒缩功能障碍患者进行检查期间，通过将肢体暴露在热室中进行冷试验：激光流量计记录提供了疾病或雷诺综合征期间发生的特定改变的数据。这些发现将有助于对血管舒缩功能障碍最有用的措施进行量化以及应用预测性测试。
