Wing R, Halme J, Sloan C S, Smith P
South Med J. 1984 May;77(5):607-10. doi: 10.1097/00007611-198405000-00017.
We analyzed 149 cases of artificial insemination with donor semen at North Carolina Memorial Hospital, Chapel Hill, to study its effectiveness. An overall pregnancy rate of 62.1% was achieved. Based on the mean monthly fecundity rate, the average monthly pregnancy rate was 16.5%, and the cumulative pregnancy rate after three, six, and ten cycles was, respectively, 40.3%, 68.5%, and 95.5%. A uniform evaluation of the women and correction of any treatable female factors before insemination contributed to a high success rate. Diagnostic laparoscopy after three to four failed insemination cycles yielded a high percentage of abnormal findings. These data suggest that almost all properly screened patients will conceive if allowed to undergo a sufficient number of inseminated cycles and that this procedure is a highly effective alternative means of circumventing male infertility.
我们分析了北卡罗来纳大学教堂山分校纪念医院的149例供精人工授精病例，以研究其有效性。总体妊娠率达到62.1%。根据平均每月受孕率，平均每月妊娠率为16.5%，三个、六个和十个周期后的累积妊娠率分别为40.3%、68.5%和95.5%。授精前对女性进行统一评估并纠正任何可治疗的女性因素有助于提高成功率。在三到四个授精周期失败后进行诊断性腹腔镜检查发现异常的比例很高。这些数据表明，几乎所有经过适当筛查的患者如果允许进行足够数量的授精周期都会受孕，并且该程序是规避男性不育的一种非常有效的替代方法。
