λ 算子位点 OL1 的 1H-NMR 研究：亚氨基和腺嘌呤 H2 共振峰的归属
1H-NMR study of the lambda operator site OL1: assignment of the imino and adenine H2 resonances.
作者信息
Weiss M A, Patel D J, Sauer R T, Karplus M
出版信息
Nucleic Acids Res. 1984 May 11;12(9):4035-47. doi: 10.1093/nar/12.9.4035.
Abstract
One- and two-dimensional proton NMR methods are being used to study the synthetic lambda operator site O-L1, a 17 base-pair DNA duplex recognized by lambda repressor and Cro protein. The complete assignment of the 17 imino protons, which participate in Watson-Crick hydrogen bonding, and of the eight adenine H2 protons, which lie in the minor groove of the double helix, is presented.
摘要
一维和二维质子核磁共振方法正用于研究合成的λ操纵基因位点O-L1，这是一段17个碱基对的DNA双链体，可被λ阻遏蛋白和Cro蛋白识别。本文给出了参与沃森-克里克氢键形成的17个亚氨基质子以及位于双螺旋小沟中的8个腺嘌呤H2质子的完整归属。
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