Alazraki N, Moitoza J, Heaphy J, Taylor A
J Nucl Med. 1984 Sep;25(9):978-81.
An animal study was performed to assess the effect on the Tc-99m phosphate bone scintigram of injury by needle aspiration or drill hole to metaphyseal and diaphyseal areas in immature and mature bones. Results showed that in 12 immature rabbits such trauma to metaphyseal regions had no effect on the bone image. Similar metaphyseal trauma in two mature dogs showed definite abnormalities on the bone image, but in one mature rabbit, no abnormality could be identified by scintigram. Diaphyseal trauma always gave a definitely abnormal bone image. Extrapolation of these results to humans should be cautious, but it suggests that needling or drilling in metaphyseal regions in neonates or young children probably does not affect later bone images.
进行了一项动物研究，以评估针吸或钻孔损伤未成熟和成熟骨骼的干骺端和骨干区域对Tc-99m磷酸盐骨闪烁显像的影响。结果显示，在12只未成熟兔中，干骺端区域的此类创伤对骨影像无影响。两只成熟犬的类似干骺端创伤在骨影像上显示出明确异常，但在一只成熟兔中，闪烁显像未发现异常。骨干创伤总是会产生明确异常的骨影像。将这些结果外推至人类时应谨慎，但这表明在新生儿或幼儿的干骺端区域进行针刺或钻孔可能不会影响后期的骨影像。
